[HTML][HTML] Molecular regulation of differentiation in early B-lymphocyte development
M Sigvardsson - International journal of molecular sciences, 2018 - mdpi.com
… B-cell differentiation [2,3,4]. Furthermore, it is now evident that the same mechanisms that
control normal B-lymphoid development in mice and humans are targeted in B-lymphoid …
control normal B-lymphoid development in mice and humans are targeted in B-lymphoid …
Molecular regulation of peripheral B cells and their progeny in immunity
MR Boothby, E Hodges, JW Thomas - Genes & development, 2019 - genesdev.cshlp.org
… In this review, we focus principally on the regulation of differentiation and functional … Origins
of and fate potential for mature B lymphoid cells. Shown is a simplified outline of the broad …
of and fate potential for mature B lymphoid cells. Shown is a simplified outline of the broad …
Transcriptional Regulation of Early B-Cell Development
… The differentiation of B cells from multipotent haematopoietic … lymphoid (ALP) and B-lymphoid
committed (BLP) progenitors … binding of complementary cis-gene regulatory elements …
committed (BLP) progenitors … binding of complementary cis-gene regulatory elements …
Epigenetic mechanisms: role in hematopoietic stem cell lineage commitment and differentiation
S Raghuwanshi, S Dahariya, R Kandi… - Current drug …, 2018 - ingentaconnect.com
… more complex than their genetic complement. Epigenetic modifications are more important
… The ectopic expression of miR-142 had no significant effect on the B-lymphoid lineage, but it …
… The ectopic expression of miR-142 had no significant effect on the B-lymphoid lineage, but it …
[HTML][HTML] Single cell characterization of B-lymphoid differentiation and leukemic cell states during chemotherapy in ETV6-RUNX1-positive pediatric leukemia identifies …
J Mehtonen, S Teppo, M Lahnalampi, A Kokko… - Genome Medicine, 2020 - Springer
… We compared normal B-lineage differentiation and in vivo leukemic cell states using single
cell RNA-sequencing (scRNA-seq) and several complementary genomics profiles. Based on …
cell RNA-sequencing (scRNA-seq) and several complementary genomics profiles. Based on …
Chromodomain helicase DNA‐binding 4 (CHD4) regulates early B cell identity and V (D) J recombination
JR Hagman, T Arends, C Laborda… - Immunological …, 2022 - Wiley Online Library
… of myeloid differentiation) genes at various stages of B cell … cell fate reprogramming: B lymphoid
progenitors become T … of the highly diverse complementarity-determining region 3 (CDR3…
progenitors become T … of the highly diverse complementarity-determining region 3 (CDR3…
[HTML][HTML] Dynamical modeling predicts an inflammation-inducible CXCR7+ B cell precursor with potential implications in lymphoid blockage pathologies
J Enciso, L Mendoza, ER Álvarez-Buylla, R Pelayo - PeerJ, 2020 - peerj.com
… The blockage at the early B lymphoid cell development … , where the disruption of basal
regulatory networks prevents the … of three modules (ig differentiation genetic core, communication …
regulatory networks prevents the … of three modules (ig differentiation genetic core, communication …
Genetic and epigenetic evolution as a contributor to WT1-mutant leukemogenesis
… A complementary DNA (cDNA) library was generated from 50 … regulation of hematopoietic
differentiation and self-renewal. … in the percentage of myeloid/B-lymphoid cells (Mac1 + Gr1 + …
differentiation and self-renewal. … in the percentage of myeloid/B-lymphoid cells (Mac1 + Gr1 + …
[HTML][HTML] An Erg-driven transcriptional program controls B cell lymphopoiesis
… regulatory network remains poorly understood. Here, we show that the transcription factor ETS
Related Gene (Erg) is essential for early B lymphoid differentiation… to complement the loss …
Related Gene (Erg) is essential for early B lymphoid differentiation… to complement the loss …
Distinct and temporary-restricted epigenetic mechanisms regulate human αβ and γδ T cell development
… regulation during T cell-lineage differentiation, we … genes. In the present study, our integrative
approach also revealed the complementarity of regulation by the different epigenetic layers …
approach also revealed the complementarity of regulation by the different epigenetic layers …